4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide

Name	BCTC
Synonyms	BCTC N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide 1-Piperazinecarboxamide, 4-(3-chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]- 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-diMethylethyl)phenyl]-1-piperazinecarboxaMide (BCTC)
CAS	393514-24-4
InChIKey	ROGUAPYLUCHQGK-UHFFFAOYSA-N

Molecular Formula	C20H25ClN4O
Molar Mass	372.89
Density	1.229±0.06 g/cm3(Predicted)
Melting Point	150-152℃
Boling Point	561.6±50.0 °C(Predicted)
Solubility	DMSO: >10mg/mL
Appearance	powder
Color	white to beige
pKa	13.95±0.70(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stord at -20°C for up to 2 months.
Sensitive	Light Sensitive

biological activity	BCTC is an oral, highly effective antagonist of vanilloid receptor 1 (VR1/TRPV1). The IC50 values of BCTC for capsaicin-induced and acid-induced VR1 activation in rats were 35 nM and 6.0 nM, respectively. BCTC has anti-tumor activity.
target	TargetValue rTRPV1 (acid-induced) (cell-free assessment) 6.0 nM rTRPV1 (capsaicin-induced) (cell-free assessment) 35 nM
Target	Value
rTRPV1 (acid-induced) (Cell-free assay)	6.0 nM
RTRPV1 (capsaicin-induced) (Cell-free assay)	35 nM

Last Update：2024-04-09 01:59:59

Spot supply

Product Name: BCTC Visit Supplier Webpage Request for quotation
CAS: 393514-24-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Spot supply

Product Name: BCTC Visit Supplier Webpage Request for quotation
CAS: 393514-24-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide Request for Quotation